In addition to heating up or cooling down fluids in just a single phase, heat exchangers can be used either to heat a liquid to evaporate (or boil) it or used as condensers to cool a vapor and condense it to a liquid. In chemical plants and refineries, reboilers used to heat incoming feed for distillation towers are often heat exchangers.

Distillation set-ups typically use condensers to condense distillate vapors back into liquid.

Power plants which have steam-driven turbines commonly use heat exchangers to boil water into steam. Heat exchangers or similar units for producing steam from water are often called boilers or steam generators.
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One of the widest uses of heat exchangers is for air conditioning of buildings and vehicles. This class of heat exchangers is commonly called air coils, or just coils due to their often-serpentine internal tubing. Liquid-to-air, or air-to-liquid HVAC coils are typically of modified crossflow arrangement. In vehicles, heat coils are often called heater cores.

On the liquid side of these heat exchangers, the common fluids are water, a water-glycol solution, steam, or a refrigerant. For heating coils, hot water and steam are the most common, and this heated fluid is supplied by boilers, for example. For cooling coils, chilled water and refrigerant are most common. Chilled water is supplied from a chiller that is potentially located very far away, but refrigerant must come from a nearby condensing unit. When a refrigerant is used, the cooling coil is the evaporator in the vapor-compression refrigeration cycle. HVAC coils that use this direct-expansion of refrigerants are commonly called DX coils.
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A spiral heat exchanger (SHE), may refer to a helical (coiled) tube configuration[8], more generally, the term refers to a pair of flat surfaces that are coiled to form the two channels in a counter-flow arragement.[9]. Each of the two channels has one long curved path. A pair of fluid ports are connected tangentially to the outer arms of the spiral, and axial ports are common, but optional.]
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Heat exchangers occur naturally in the circulation system of fish and whales. Arteries to the skin carrying warm blood are intertwined with veins from the skin carrying cold blood, causing the warm arterial blood to exchange heat with the cold venous blood. This reduces the overall heat loss in cold waters. Heat exchangers are also present in the tongue of baleen whales as large volumes of water flow through their mouths. Wading birds use a similar system to limit heat losses from their body through their legs into the water.
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Heat exchangers are widely used in industry both for cooling and heating large scale industrial processes. The type and size of heat exchanger used can be tailored to suit a process depending on the type of fluid, its phase, temperature, density, viscosity, pressures, chemical composition and various other thermodynamic properties.

In many industrial processes there is waste of energy or a heat stream that is being exhausted, heat exchangers can be used to recover this heat and put it to use by heating a different stream in the process. This practice saves a lot of money in industry as the heat supplied to other streams from the heat exchangers would otherwise come from an external source which is more expensive and more harmful to the environment.
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